NCTF 135HA is a French-made mesotherapy skin booster containing hyaluronic acid, 12 vitamins, 24 amino acids, minerals, and antioxidants, injected in fine micro-doses to boost hydration, collagen, and skin radiance. Nicknamed the “Chanel Injection,” it’s popular in Malaysia for dull, dehydrated, or aging skin, taking 30–45 minutes per session with minimal downtime over a course of 3–5 treatments.
What Is NCTF 135HA?
What NCTF stands for and what it’s used for
NCTF stands for New Cellular Treatment Factor. Manufactured by FILLMED Laboratories in France, NCTF 135HA — nicknamed the “Chanel Injection” — is a poly-revitalizing solution used for mesotherapy. It targets skin aging at the cellular level, focusing on revitalization rather than just filling. It’s primarily used to treat the face, neck, decolletage, and hands to restore biological youthfulness.
Key ingredients in NCTF 135HA
This powerhouse cocktail contains 59 active ingredients plus hyaluronic acid (HA). It includes 12 vitamins (like A, B, C, and E), 24 amino acids to boost protein synthesis, 6 minerals, 6 coenzymes, 5 nucleic acids, and 2 antioxidants — essentially a “superfood” for your dermal cells.
How it improves skin quality — what the clinical evidence shows
By providing the essential building blocks for cellular function, NCTF 135HA stimulates fibroblast activity, increasing collagen and elastin production. A randomized, controlled multicenter study of 146 patients tested a 3-session NCTF 135HA protocol against a control anti-aging cream and found significantly reduced wrinkles across the crow’s feet, neck, and décolleté at both Day 75 and Day 120, alongside a significant increase in skin hydration measured just 7 days after the final injection and improved facial radiance scores compared with the cream-only group — a biological improvement in skin quality that topical serums alone haven’t matched in this trial.
Who Is a Good Candidate for NCTF 135HA?
NCTF 135HA is suitable for both men and women across most skin types. It’s best suited to those with:
- Dull, dehydrated, or tired-looking skin
- Uneven skin tone or rough, congested texture
- Early fine lines caused by dehydration rather than deep muscle movement
- General loss of radiance or “tiredness” despite adequate sleep
- A preference for a biological, cellular-level approach over topical skincare alone
It’s not a substitute for volume-based treatments (for hollowing or significant structural sagging) or for muscle-related dynamic wrinkles, and it’s not recommended during pregnancy or breastfeeding, or for those with active skin infections. If you’re comparing skin boosters generally, our types of skin boosters guide covers where NCTF fits among the other options available in Malaysia.
Benefits of NCTF 135HA
Deep skin hydration
The high-concentration HA in this formula acts as a moisture magnet. Unlike topical moisturizers, it delivers hydration directly into the dermis, giving you a plumped, dewy look that builds progressively over your treatment course — a common concern for dry or dehydrated skin in Malaysia’s humid, air-conditioned indoor environments.
Improves skin elasticity and firmness
As we age, our skin loses its “snap.” The amino acids and vitamins in NCTF 135HA help restructure the dermal matrix. By reinforcing the skin’s support system, it increases elasticity and helps saggy skin feel tighter and more resilient against gravity and daily facial expressions.
Reduces fine lines and wrinkles
This treatment is excellent for smoothing out “crepey” skin. While not a muscle relaxant like Botox, it softens fine lines by improving skin density. It’s particularly effective for those tiny, stubborn wrinkles around the eyes and mouth that are caused by dehydration and collagen loss.
Restores skin radiance
If your skin looks “tired” or sallow, this is your solution. It promotes microcirculation and cellular metabolism, improving oxygenation and resulting in a brighter, more even tone — the kind of luminous, low-makeup finish often described as glass skin.
What Skin Concerns Can NCTF 135HA Treat?
Dehydrated and dull skin
Chronic dryness often leads to a lackluster appearance. NCTF 135HA treats the root cause by restoring the skin’s hydro-balance. It’s a favorite in Malaysia’s humid climate, where air conditioning frequently strips the skin of its natural moisture, leaving it looking dull and fatigued.
Fine lines and early ageing
It is a proactive tool for “pre-juvenation.” For those in their 20s or 30s, it stalls the aging process by maintaining high collagen levels. For older patients, it helps repair existing damage, making it a versatile anti-aging option for various life stages.
Uneven skin texture and acne scarring
Enlarged pores and rough patches can make makeup application difficult. The revitalizing cocktail refines the skin’s grain by encouraging healthy cell turnover. Because it stimulates collagen and cell renewal, NCTF 135HA is also used — often alongside other regenerative treatments — to soften the appearance of post-inflammatory pigmentation and shallow acne scarring as part of a broader acne scar treatment plan, though deeper or textured scars typically need dedicated resurfacing approaches on top of it.
Dark circles and periorbital pigmentation
NCTF 135HA is increasingly used around the eyes for thin, tired-looking under-eye skin and periorbital pigmentation, since it improves skin quality and microcirculation without adding volume. It’s best suited to dark circles caused by thin skin, dehydration, or pigmentation rather than hollowing — for hollow or structural dark circles, it’s often paired with volume-based approaches instead.
Loss of firmness and glow
When the skin loses its ability to reflect light, it looks aged. By thickening the dermis and improving the epidermis’s health, NCTF 135HA restores that youthful “lit-from-within” quality.
How NCTF 135HA Treatment Works
Injection procedure
The procedure involves multiple micro-injections into the superficial dermis using a very fine needle or a microneedling device. Some practitioners use the “Nappage” technique. A topical numbing cream is usually applied first to ensure the experience is virtually painless and comfortable for the patient.
Treatment duration
A session is remarkably quick, typically taking only 30 to 45 minutes, including the time needed for the numbing cream to take effect. Because it’s so efficient, many professionals in Malaysia’s urban centers schedule this as a “lunchtime” procedure for busy working adults.
Aftercare and downtime
Downtime is minimal. You may experience tiny “papules” (small bumps) or redness at the injection sites, which typically subside within 24 hours. It is advised to avoid heavy exercise, saunas, and direct sun exposure for at least 48 hours to allow the skin to heal optimally.
NCTF 135HA Results, Before & After, and Duration
When results become visible
While some notice a “refresh” immediately, the true magic happens after a few days. As the ingredients stimulate cellular repair, you’ll see improved hydration and glow within a week. The full biological effect on skin texture and firmness peaks after a series of treatments.
Before and after what to expect
Across a full protocol, patients typically notice progressively plumper, more even-toned skin with reduced fine lines around the eyes — consistent with the wrinkle-reduction and radiance improvements seen in clinical trial photography. Ask your clinic for their own before-and-after gallery during consultation so you can set realistic expectations for your skin type and concern.
How long results last
The results of a single session can last for several weeks, but the cumulative effects of a full protocol last much longer. Generally, the improved skin quality is maintained for 3 to 6 months after the initial phase, depending on your lifestyle and sun protection habits.
Recommended treatment sessions
For the best long-term results, a protocol of 3 to 5 sessions is recommended. These are usually spaced 2 to 3 weeks apart. Afterward, a maintenance session every 3 to 6 months is suggested to keep the skin in its peak “revitalized” state.
NCTF 135HA vs Rejuran: What’s the Difference?
Both are injectable skin-quality treatments popular in Malaysia, but they work differently. Rejuran uses polynucleotides (PN) derived from salmon DNA to trigger tissue repair and wound-healing pathways, making it especially well-regarded for acne scars and overall skin regeneration. NCTF 135HA instead delivers a concentrated cocktail of vitamins, amino acids, minerals, and hyaluronic acid to nourish and hydrate skin cells directly. In practice, NCTF tends to produce a faster, more visible “glow” after a single session, while Rejuran’s repair-focused effects build more gradually. Many patients use both as part of a rotating skin-quality program rather than choosing one over the other — see our full skin booster vs Rejuran comparison for more detail, or ask your doctor about sequencing based on your main concern.
NCTF 135HA Price in Malaysia
Average cost per session
In Malaysia, the cost for a single session of NCTF 135HA generally ranges from RM 1,100 to RM 1,300. Some high-end aesthetic centers may charge more if the treatment is combined with other modalities like laser therapy or specialized skin boosters for enhanced results.
Factors affecting price
The total cost depends on the area treated and the number of vials used. Additionally, the practitioner’s expertise and the clinic’s location play a role. Always ensure you are receiving the authentic Fillmed product — you can confirm the manufacturer’s official information on FILLMED’s NCTF 135HA product page — as counterfeit solutions can be cheaper but dangerous.
Safety and Side Effects
Common side effects
Side effects are generally mild and temporary. These include slight swelling, bruising, or pinpoint bleeding at the injection sites. A broader clinical assessment of HA-based skin boosters as a treatment class reports a generally favorable safety profile across trial follow-up periods, consistent with what’s seen with NCTF 135HA in practice. Because the components are naturally found in the body or are biocompatible, allergic reactions are extremely rare, making it a very safe option for most skin types.
Risks and precautions
As with any injectable, there is a minor risk of infection if aftercare isn’t followed. This treatment is not recommended for pregnant or breastfeeding women, or those with active skin infections. Always consult a qualified medical professional to ensure you are a suitable candidate for the procedure.
Frequently Asked Questions
Is NCTF 135HA safe?
Yes, it is highly safe. It has been used globally for over 40 years and carries a CE mark for safety and efficacy. The formula is rigorously tested to ensure high purity, making it one of the most trusted skin boosters in the aesthetic industry.
How many sessions are needed?
For transformative results, an initial “attack” phase of 3 sessions is standard. This builds up the skin’s nutrient reservoir. Patients with more significant sun damage or aging may benefit from up to 5 sessions to fully restore the skin’s structural integrity and radiance.
When will I see results?
Visible improvements in hydration and “glow” usually appear within 3 to 5 days. For improvements in fine lines and skin firmness, you will see a progressive change over the course of your treatment plan as new collagen fibers are synthesized.
Can NCTF 135HA help with dark circles?
Yes, for dark circles caused by thin skin, dehydration, or pigmentation — it improves skin quality without adding volume. It’s less effective on its own for hollow, structural dark circles, which usually respond better to volume-based treatments. See our full dark eye circle treatment guide to identify which type you have.
Is NCTF 135HA or Rejuran better for acne scars?
Rejuran is generally the stronger option for acne scars specifically, since its polynucleotide mechanism is more targeted at tissue repair. NCTF 135HA can still help with overall texture and post-inflammatory pigmentation, and the two are sometimes used together as part of a broader acne scar treatment plan.
Who should not get NCTF 135HA?
It’s not recommended for pregnant or breastfeeding women, or anyone with active skin infections in the treatment area. Patients seeking correction of hollowing or significant structural sagging should discuss volume-based alternatives with their doctor instead.
