Rejuran treatment is a polynucleotide (PN) injectable designed to repair and rejuvenate skin at a cellular level. It supports collagen production, improves hydration, reduces fine lines, and enhances overall skin texture. It’s suitable for sensitive or damaged skin, acne scars, early signs of aging, and global skin health improvement.
What Is Rejuran?
Rejuran is a skin treatment that focuses on repairing skin from within, rather than adding volume or freezing muscles. Its main ingredient is polynucleotides (PN), purified DNA fragments from salmon, carefully processed for high compatibility with human skin. PN promotes dermal regeneration, strengthens the skin barrier, and improves microcirculation.
Unlike fillers or skin boosters, Rejuran works gradually, restoring natural skin function and resilience over time.
How Rejuran Works in the Skin
Rejuran stimulates the skin’s natural healing processes:
Activates fibroblasts to produce collagen and elastin
Improves microcirculation for better nutrient delivery
Strengthens the skin barrier, locking in hydration
Reduces inflammation, calming sensitive or reactive skin
By repairing the skin at a cellular level, Rejuran creates long-lasting improvements in texture, elasticity, and overall skin health.
Key Rejuran Benefits
1. Smooths Skin Texture
Rejuran improves uneven or rough skin, including post-acne scars and early signs of aging. Pores appear refined, and the skin surface feels soft and healthy.
2. Boosts Hydration From Within
By strengthening the skin barrier, Rejuran helps skin retain moisture naturally, reducing dryness, tightness, and dullness. Unlike hyaluronic acid alone, it enhances internal hydration for lasting glow.
3. Reduces Fine Lines and Early Wrinkles
Through fibroblast activation and collagen stimulation, Rejuran gradually softens fine lines, particularly around the eyes and forehead, while keeping results natural-looking.
4. Supports Acne Scar Repair
Rejuran accelerates healing, improves texture, and reduces redness associated with acne scars. While not a replacement for lasers or microneedling, it enhances recovery and skin quality.
5. Calms Sensitive or Damaged Skin
Polynucleotides have anti-inflammatory properties, helping to strengthen fragile or reactive skin. It’s also used post-procedure to reduce irritation and support faster recovery.
6. Enhances Overall Skin Health
Rejuran improves skin elasticity, tone, and resilience, making it ideal for preventive anti-aging treatments and global skin rejuvenation.
Rejuran vs Other Injectables
Rejuran vs Dermal Fillers
Fillers add volume; Rejuran repairs skin
No change to facial shape or contour
Rejuran vs Skin Boosters
Skin boosters hydrate superficially; Rejuran stimulates regeneration and collagen
Often combined for enhanced results
Treatment Areas
Commonly treated areas include:
Face: under eyes, cheeks, forehead
Neck
Hands
These regions benefit most from repair and rejuvenation rather than volume replacement.
Treatment Timeline and Results
Sessions: Typically 2–3 sessions spaced 3–4 weeks apart
Initial results: Noticeable within 2–3 weeks
Full effect: 6–12 weeks, improving gradually over time
Maintenance: Recommended every 6–12 months depending on skin condition and lifestyle
Downtime is minimal. Mild swelling, redness, or small bumps may appear but usually resolve within a few days.
Safety and Considerations
Rejuran is well-tolerated when administered by trained professionals. Allergic reactions are rare due to high biocompatibility. Topical numbing is commonly used, and patients can resume daily activities immediately.
Good candidates include those who want natural skin improvement, have early signs of aging, or wish to enhance skin quality after procedures. It is not intended for significant lifting or volumizing effects.
Frequently Asked Questions
Is Rejuran the same as salmon DNA?
Rejuran contains purified polynucleotides, not raw DNA, processed to be safe and compatible with human skin.
Does Rejuran make the face look fuller?
No. Rejuran does not add volume; it improves skin health, texture, and elasticity.
How many sessions are recommended?
Most patients undergo 2–3 sessions, spaced 3–4 weeks apart for optimal results.
Can it help pigmentation or only texture?
Rejuran improves overall skin quality, including redness and mild pigmentation, while enhancing texture.
Is it suitable for sensitive skin?
Yes. Its anti-inflammatory properties make it suitable for reactive or fragile skin and for recovery after procedures.
When will I see results?
Early improvements can appear within 2–3 weeks, with continued enhancement over several months.
Can it be combined with other treatments?
Yes. It is often combined with microneedling or laser procedures to support skin repair and recovery.
